Enzymes in the glutamate-glutamine cycle in the anterior cingulate cortex in postmortem brain of subjects with autism

Table 2 Results from correlation analyses between age of donors and expression levels of proteins and amino acids

		KGA	LGA	GS	GDH1	GDH2	GFAP	NSE	Glu	Gln	Glu/Gln
Total sample (n = 20)	Pearson r correlation coefficient	-.14	.10	-.13	-.04	.20	-.25	.22	.09	.35	-.32
	P- value	.56	.68	.58	.87	.39	.29	.35	.72	.13	.17
Control (n = 13)	Pearson r correlation coefficient	-.24	.00	-.30	-.07	-.07	-.44	.37	.34	.54	-.48
	P- value	.42	.98	.32	.81	.80	.12	.21	.25	.06	.09
Autism (n = 7)	Pearson r correlation coefficient	.22	-.13	-.05	.05	.29	.14	.56	-.05	.07	-.16
	P-value	.66	.78	.91	.90	.56	.78	.20	.90	.90	.71

Abbreviations: GDH1, glutamate dehydrogenase 1; GDH2, glutamate dehydrogenase 2; GFAP, glial fibrillary acidic protein; Gln, glutamine; Glu, glutamate; GS, glutamine synthetase; KGA, kidney-type glutaminase; LGA, liver-type glutaminase; NSE, neuron-specific enolase.