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Figure 1 | Molecular Autism

Figure 1

From: Enzymes in the glutamate-glutamine cycle in the anterior cingulate cortex in postmortem brain of subjects with autism

Figure 1

Expression levels of enzymes associated with the glutamate-glutamine cycle. (A) Scatter plots of enzyme optical density values for control subjects (n = 13) and individuals with autism (n = 7). Results are expressed as a percent of the control values, normalized by the β-actin level. (B) Western blots showing immunolabeling of KGA, LGA, GS, GDH1, GDH2, GFAP, NSE, and β-actin in the anterior cingulate cortex (ACC) of control subjects (n = 13) and individuals with autism (n = 7). Abbreviations: GDH1, glutamate dehydrogenase 1; GDH2, glutamate dehydrogenase 2; GFAP, glial fibrillary acidic protein; GS, glutamine synthetase; KGA, kidney-type glutaminase; LGA, liver-type glutaminase; NSE, neuron-specific enolase.

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