Table 1 Coverage summary of mTOR pathway candidate genes sequenced by next generation sequencing
From: Lack of association of rare functional variants in TSC1/TSC2 genes with autism spectrum disorder
Gene | Chromosome | Exons screened | Targeted exon bases | High coverage basesa | Average coverage per pool | Average coverage per probandb | Average coverage per parentb |
|---|---|---|---|---|---|---|---|
TSC1 | 9 | Exons 3-23 | 3495 | 3495 | 52804.6 | 1760.2 | 880.1 |
TSC2 | 16 | Exons 1-41 | 5355 | 5355 | 79732.3 | 2657.7 | 1328.9 |
RHEB | 7 | Exons 2-8 | 555 | 503 | 16050.2 | 535 | 267.5 |
MYCBP2 (Pam) | 13 | Exons 1-83 | 13923 | 13923 | 21906.8 | 730.2 | 365.1 |
FBXO45 | 3 | Exons 1-3 | 861 | 858 | 33853.7 | 1128.5 | 564.2 |