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Table 1 Coverage summary of mTOR pathway candidate genes sequenced by next generation sequencing

From: Lack of association of rare functional variants in TSC1/TSC2 genes with autism spectrum disorder

Gene Chromosome Exons screened Targeted exon bases High coverage basesa Average coverage per pool Average coverage per probandb Average coverage per parentb
TSC1 9 Exons 3-23 3495 3495 52804.6 1760.2 880.1
TSC2 16 Exons 1-41 5355 5355 79732.3 2657.7 1328.9
RHEB 7 Exons 2-8 555 503 16050.2 535 267.5
MYCBP2 (Pam) 13 Exons 1-83 13923 13923 21906.8 730.2 365.1
FBXO45 3 Exons 1-3 861 858 33853.7 1128.5 564.2
  1. aindividual bases for which at least 3000x average coverage was obtained.
  2. bstatistics reflect coverage per proband/parent sample, not per chromosome.