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Table 4 Significant SNPs and SNP-SNP pairs

From: Genetic variation in GABRB3 is associated with Asperger syndrome and multiple endophenotypes relevant to autism

SNP or SNP-SNP interaction Phenotype P values (uncorrected)a Minor allele/major alleleb MAF (HapMap CEPH)c Frequency of minor allele χ2
Cases Controls  
rs7180158 AS 3.58E-04 A/G A = 0.24 0.1624 0.08272 12.74
rs7165604 AS 4.51E-04 C/T C = 0.17 0.1174 0.05145 12.31
rs12593579 AS 6.68E-04 C/A C = 0.21 0.194 0.1093 11.58
rs11636966 EQ 5.94E-04 T/C T = 0.22 NA NA NA
rs9806546 EQ 1.47E-03 A/G A = 0.40 NA NA NA
rs12438141-rs1035751 EFT 7.59E-06 C/T - A/G T = 0.13, G = 0.06 NA NA NA
rs12438141-rs7179514 EFT 5.21E-06 C/T - C/G T = 0.13, G = 0.31 NA NA NA
rs7174437-rs1863455 MRT 1.58E-05 C/T - C/T C = 0.12, C = 0.08 NA NA NA
  1. Abbreviations: AQ, Autism Spectrum Quotient; AS, Asperger syndrome; EFT, Embedded Figures Test; EQ, Empathy Quotient; MRT, Mental Rotation Test; NA, not applicable; SNP, single nucleotide polymorphism.
  2. aCorrected P-value threshold is 3.6 × 10-05.
  3. bAlleles for SNP-SNP pairs have been provided in the order they are written.
  4. cMAF for SNP-SNP pairs have been provided in the order they are written.