Table 4 Risk factors of autism in the AGRE sample according to epilepsy
Risk factors | Â | Total (n) | Epilepsy (n) | No epilepsy (n) |
|---|---|---|---|---|
Total of individuals | 478 | 63 | 415 | |
Chromosomal abnormality or genetic condition | 14 (2.92%) | 4 (6.35%) | 10 (2.4%) | |
| Â | 16p11.2 deletion/duplication | 4 | 2 | 2 |
|  | 15q11–13 duplication | 3 | 1 | 2 |
| Â | 22q11.21 duplication | 1 | 0 | 1 |
| Â | 22q13.33 duplication | 1 | 0 | 1 |
| Â | t(2;9)(p13;q34.3) | 1 | 1 | 0 |
| Â | Mosaic t(3;16) | 1 | 0 | 1 |
| Â | Mosaic t(3;14) | 1 | 0 | 1 |
| Â | Trisomy 21 | 1 | 0 | 1 |
| Â | Mosaic trisomy 12 | 1 | 0 | 1 |
Prematuritya/pre- or perinatal insult | 19 (3.98%) | 3 (4.76%) | 16 (3.9%) | |
Cerebral palsy | Â | 2 (0.42%) | 0 | 2 (0.48%) |
Abnormal cerebral imaging | 3 (0.63%) | 2 (3.17%) | 1 (0.24%) | |
| Â | Agenesis of corpus callosum | 1 | 1 | 0 |
| Â | Left frontal damage | 1 | 1 | 0 |
| Â | Not given | 1 | 0 | 1 |
Other significant abnormality | 4 (0.84%) | 1 (1.59%) | 3 (0.72%) | |
| Â | Significant dysmorphology | 2 | 0 | 2 |
| Â | Mitochondrial disorder, mild tonsillectomy (premature puberty) | 1 | 1 | 0 |
| Â | Cranial nerve paralysis (congenital versus traumatic) | 1 | 0 | 1 |
Total of individuals with abnormalitiesb | 42 (8.8%) | 10 (15.9%) | 32 (7.71%) | |