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Figure 1 | Molecular Autism

Figure 1

From: Phosphorylated fragile X mental retardation protein at serine 499, is reduced in cerebellar vermis and superior frontal cortex of subjects with autism: implications for fragile X mental retardation protein-metabotropic glutamate receptor 5 signaling

Figure 1

Ratios of serine 499 phosphorylated Fragile X mental retardation protein (FMRP)/neuronal specific enolase (NSE) in the cerebellar vermis and Brodman area 9 (BA9) of subjects with autism versus matched controls. Significant reductions were found in subjects with autism in the vermis of adults (P <0.012) and children ( P <0.0018), and in BA9 in adults (P <0.0001).

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