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Figure 3 | Molecular Autism

Figure 3

From: Differential recruitment of coregulators to the RORA promoter adds another layer of complexity to gene (dys) regulation by sex hormones in autism

Figure 3

Co-immunoprecipitation analysis of AR/ERα coregulators. Whole-cell lysates of SH-SY5Y cells treated with 1nM DHT (A) or 1nM E2 (B) for 2 hours were immunoprecipitated with anti-NCOA1, anti-NCOA5, anti-SUMO1, anti-FHL2, or IgG antibody. Western blot analyses were performed to determine the enrichment of AR (A) and ERα (B) in the immunoprecipitated complexes. AR, androgen receptor; DHT, 4,5α-dihydrotestosterone; E2, 17β-estradiol; ERα, estrogen receptor alpha.

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Molecular Autism

ISSN: 2040-2392