Figure 4

Examples of MeCP2 binding enrichment at specific gene regions. (A) MeCP2 binding at the TSS of Aard. (B) MeCP2 binding throughout the gene body of Slc38a1. (C) MeCP2 binding at the TES of Armc3. Cumulative DNA sequences co-purified with MeCP2 from wild-type astrocyte chromatin are depicted as wiggle tracks aligned to the UCSC genome browser NCBI37/mm9 track of the C57BL6/J mouse genome. Read counts are shown on the Y axis. MeCP2, methyl-CpG-binding protein 2; TES, transcriptional end site; TTS, transcriptional start sites.