Figure 2

A heat map showing gene expression levels of 119 transcripts including MeCP2 differentially regulated between astrocytes with Mecp2 /MeCP2 deficiency and wild-type astrocytes at P < 0.005 and 1.2 fold change threshold. Each column corresponds to individual astrocyte samples (WT: wild-type astrocytes; KO: Mecp2/MeCP2-deficient astrocytes). Each row represents an individual gene. Expression signal intensity was color-coded with red being high and green being low, as shown by the bar to the right. The tree structures to the left and on the top demonstrated similarities between genes and samples, respectively, according to Pearson cluster analysis results. Thus the more similar, the smaller the distance between the tree branches. MeCP2, methyl-CpG-binding protein 2.