Skip to main content

Advertisement

Table 1 Multiplex immunoassay analysis identification of proteins significantly altered in autism spectrum disorders (ASD)

From: Identification of an age-dependent biomarker signature in children and adolescents with autism spectrum disorders

Analytes P value Fold changea
Tamm-Horsfall urinary glycoprotein 0.004 1.18
Interleukin-3 0.010 0.79
von Willebrand factor 0.023 1.16
Interleukin 12 subunit p40 0.025 0.87
Tyrosine kinase with Ig and EGF homology domains 2 0.033 1.09
Tumor necrosis factor beta 0.034 1.18
Interleukin-13 0.038 0.86
Macrophage derived chemokine 0.042 0.92
Stem cell factor 0.050 0.89
  1. aGeometric means were used to calculate fold changes (ASD/control) in ASD individuals (n = 37) compared to control (n = 37) subjects. There were no significant differences in age (ASD = 10.9 ± 3.4 years; control = 10.3 ± 3.0 years) or body mass index (BMI) (ASD = 18.0 ± 3.5 kg/m2, control = 17.7 ± 3.1 kg/m2). Autism Spectrum Quotient (AQ) scores were significantly different (ASD = 92.0 ± 20; control = 43.9 ± 18; P <0.001). See Table 2 for more detailed demographics. Demographics are reported as mean ± standard deviation.