Comparison of white matter integrity between autism spectrum disorder subjects and typically developing individuals: a meta-analysis of diffusion tensor imaging tractography studies

Table 3 Meta-analysis by tract and value

Tract	Laterality	Value	Number of dataset	N ^a	N ^b	Lower 95% CI	Upper 95% CI	Z value	P value	HeterogeneityI²	Publication bias
Corpus callosum	NA	FA	9	208	179	−1.087	−0.081	−2.275	0.023	81.91	0.541
Corpus callosum	NA	MD	6	129	125	0.163	0.950	2.770	0.006	53.81	0.650
Urinate fasciculus	Left	FA	6	117	125	−0.872	−0.115	−2.553	0.011	49.76	0.279
	Left	MD	4	60	75	−0.148	1.300	1.584	0.113	73.96	0.682
	Right	FA	6	116	124	−0.998	0.203	−1.237	0.216	75.81	0.027
	Right	MD	4	60	75	0.123	−0.410	0.963	0.790	69.11	0.636
Cingulum	Left	FA	5	101	109	−0.846	0.224	−1.139	0.255	69.80	0.633
Cingulum	Right	FA	5	101	109	−00.475	0.525	0.099	0.921	65.94	0.857
Superior longitudinal fasciculus	Left	FA	5	96	86	−0.954	−0.097	−2.404	0.016	48.34	0.707
	Left	MD	4	51	58	0.062	1.256	2.163	0.031	49.66	0.950
	Right	FA	5	92	82	−0.682	0.158	−1.229	0.219	43.99	0.462
	Right	MD	4	51	58	0.140	1.100	2.534	0.011	26.11	0.499
Inferior longitudinal fasciculus	Left	FA	4	61	85	−1.491	0.313	−1.279	0.201	83.19	0.907
Inferior longitudinal fasciculus	Right	FA	4	61	85	−0.775	0.000	−1.959	0.050	20.15	0.207
Inferior frontal occipital fasciculus	Left	FA	3	68	76	−0.979	0.195	−1.309	0.191	63.22	0.690
	Right	FA	3	68	76	−0.735	0.152	−1.287	0.198	37.41	0.528

^aNumber of ASD participants. ^bNumber of controls. ASD autism spectrum disorder, CI confidence interval, FA fractional anisotropy, MD mean diffusivity.

ISSN: 2040-2392