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Table 1 Clinical characteristics of control individuals and subjects with high-functioning ASD
| Group | Control (number = 29) | ASD (number = 22) | P-value |
|---|---|---|---|
| Age, years | 11.6 ± 1.9 (8 to 16) | 11.5 ± 3.2 (5 to 17) | NS |
| Weight, kg | 40 ± 9.9 (24 to 57.6) | 41.4 ± 16.5 (17.5 to 96.6) | NS |
| Height, cm | 149.3 ± 11.9 (121.4 to 167) | 147 ± 18.3 (110 to 178) | NS |
| BMI, kg/m2 | 17.7 ± 2.3 (14.4 to 25.3) | 18.5 ± 3.5 (13.9 to 30.5) | NS |
| CRP, mg/dl | 0.02 ± 0.02 (0.01 to 0.08) | 0.13 ± 0.44 (0.01 to 2.30) | NS |
| ADI-R | |||
| Domain A score | N/A | 20.7 ± 5.0 (10 to 27) | |
| Domain BV score | N/A | 14.2 ± 4.2 (8 to 21) | |
| Domain C score | N/A | 5.3 ± 2.0 (3 to 9) | |
| Domain D score | N/A | 3.2 ± 1.0 (2 to 5) | |
| Sum | N/A | 43.5 ± 9.6 (28– to 0) | |
| WISC-III | |||
| Full-scale IQ | 103.5 ± 13.1 (82 to 129) | 97.2 ± 17.7 (72 to 134) | NS |
| Adhesion molecules | |||
| sPECAM-1 (ng/ml) | 77.8 ± 13.2 (41.9 to 99.3) | 58.4 ± 12.5 (36.4 to 82.4) | <0.0001 |
| sE-Selectin (micro g/ml) | 44.8 ± 13.2 (24.1 to 89.7) | 42.9 ± 19.1 (13.1 to 93.2) | NS |
| sP-Selectin (micro g/ml) | 69.5 ± 21.2 (38.9 to 125.5) | 78.1 ± 28.9 (39 to 137.5) | NS |
| sICAM-1 (micro g/ml) | 325.8 ± 41.5 (243.8 to 422.1) | 323.3 ± 56.4 (223.5 to 428.2) | NS |
| sVCAM-1 (micro g/ml) | 916.5 ± 106.6 (749.4 to 1160.8) | 810.5 ± 146.8 (561.8 to 1162.5) | 0.0042 |
