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Table 6 Association between deletion size and phenotypic variables

From: Prospective investigation of autism and genotype-phenotype correlations in 22q13 deletion syndrome and SHANK3 deficiency

Phenotypic variable N Deletion size BCa confidence intervala
Lower Upper
Number of dysmorphic features 32 0.474b 0.145 0.738
Number of medical comorbidities 32 0.386b 0.022 0.640
Nonverbal IQ estimate 29 −0.332 −0.640 0.112
Gross motor skills (Vineland) 31 −0.402c −0.728 0.036
Fine motor skills (Vineland) 31 −0.123 −0.473 0.254
Expressive language skills (Vineland) 32 −0.184 −0.531 0.199
Receptive language skills (Vineland) 32 −0.231 −0.553 0.154
Qualitative abnormalities in reciprocal social interactions (ADI-R) 30 0.466b 0.073 0.723
Qualitative abnormalities in communication (ADI-R) 30 0.498b 0.091 0.740
Restricted, repetitive, and stereotyped patterns of behavior (ADI-R) 30 −0.229 −0.592 0.214
  1. aBooststrap estimates and bias corrected and accelerated confidence intervals for Spearman rank order correlations; bsignificant at 0.05 level (two-tailed test) as confidence interval does not contain 0; capproached significance at 0.05 level (two-tailed test). ADI-R, Autism Diagnostic Interview-Revised; BCa, bias corrected and accelerated confidence intervals; IQ, intelligence quotient.