Figure 1
From: Evidence of novel fine-scale structural variation at autism spectrum disorder candidate loci
A deletion of approximately 70 kb encompassing two exons (3,4) from the NRXN1 gene (alpha-1-isoform). Previously reported NRXN1 CNV events in ASD cases are shown mapped below [38–40, 42–49]. A subset of NRXN1 structural variants reported in individuals with mild to severe intellectual disability is also depicted [49]. Solid lines indicate deletions (majority) and dashed lines indicate duplication events.