Brain region-specific altered expression and association of mitochondria-related genes in autism

Table 4 FBAT analysis of SLC25A27 in Japanese family samples

Marker	Location	Allele^a	Families^b	Frequency	Z-score^c	P value^d
rs12192544	5’	C	68	0.888	0.000	1.000
		G		0.112	0.000
rs9381469	Intron 3	G	138	0.532	0.147	0.883
		A		0.468	−0.147
rs6901132	Intron 4	A	132	0.573	0.899	0.368
		G		0.427	−0.899
rs6901178	Intron 4	G	61	0.896	−1.990	*0.046*
		A		0.104	1.990
rs2270450	Exon 9 UTR	C	109	0.771	0.877	0.380
		T		0.229	−0.877
P value after multimarker testing						0.073

^aMajor allele is listed first; ^bNumber of informative families used by FBAT; ^cPositive score indicates the risk allele, negative score indicates the protective allele; ^dP <0.05, additive model, significant P values are indicated in bold italics; UTR, Untranslated region.

ISSN: 2040-2392