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Table 2 The individual SNP genotypes versus RBS-R subscale and sum mean scores

From: A quantitative association study of SLC25A12 and restricted repetitive behavior traits in autism spectrum disorders

UIC-UF sample (n = 179 probands)

SNP

rs2056202

rs2056202

rs2056202

rs908670

rs908670

rs908670

rs2292813

rs2292813

rs2292813

Genotypea

A/A

A/G

G/G

G/G

G/A

A/A

A/A

A/G

G/G

Nb

6

66

106

15

76

86

3

52

124

Stereotyped behavior

5.5 ± 3.4

6.6 ± 4

5.3 ± 3.5

7.1 ± 4.6

5.5 ± 3.7

5.8 ± 3.6

4.3 ± 3.2

6.9 ± 3.9

5.4 ± 3.6

Self-injurious behavior

2.2 ± 1.9

4.8 ± 5.6

3.1 ± 3.9

4.2 ± 6.4

3.1 ± 4.2

4.3 ± 4.8

2.3 ± 1.5

5.1 ± 5.7

3.2 ± 4.2

Compulsive behavior

6.5 ± 6.2

6.7 ± 5.3

6.4 ± 5.3

9.5 ± 7.9

6 ± 4.7

6.2 ± 5

4.3 ± 4

7.4 ± 5.6

6.1 ± 5.2

Ritualistic behavior

4.8 ± 3.7

8.3 ± 5.5 c

5.9 ± 4.2

6.1 ± 4.8

6.4 ± 4.8

7 ± 5

3.3 ± 3.5

8.8 ± 5.3 d

5.9 ± 4.4

Sameness behavior

10.2 ± 8.3

12.9 ± 8.6

9.9 ± 6.6

10.5 ± 7.5

10.4 ± 7.1

11.5 ± 7.8

10 ± 11.4

13.8 ± 8.7 d

9.9 ± 6.7

Restricted behavior

3.7 ± 3.6

5.8 ± 3.4

4.9 ± 3.1

5.1 ± 3.6

5.1 ± 3.5

5.4 ± 3.1

3.3 ± 3.2

6.3 ± 3.4

4.8 ± 3.2

Sum

32.8 ± 21.9

45.8 ± 26.5

35.4 ± 19.6

42.6 ± 24.5

36 ± 21.8

41.2 ± 23.2

27.7 ± 22.7

48.5 ± 26d

35.5 ± 20.2

SSC sample (n = 720 probands)

SNP

rs2056202

rs2056202

rs2056202

rs908670

rs908670

rs908670

rs2292813

rs2292813

rs2292813

Genotypea

A/A

A/G

G/G

G/G

G/A

A/A

A/A

A/G

G/G

Nb

21

176

523

67

284

367

10

127

583

Stereotyped behavior

6 ± 3.6 d

4.4 ± 3.2

4 ± 3.1

3.3 ± 2.8

4.1 ± 3

4.4 ± 3.3 d

5.6 ± 3.8

4.2 ± 2.9

4.1 ± 3.2

Self-injurious behavior

3.8 ± 4.5 d

2.1 ± 2.9

1.9 ± 2.6

1.4 ± 2

1.8 ± 2.4

2.3 ± 3.1 d

2.8 ± 3

2 ± 2.6

2 ± 2.8

Compulsive behavior

5.5 ± 4.8

4.3 ± 3.9

4 ± 3.7

3.3 ± 3

4.1 ± 4

4.3 ± 3.8

5.7 ± 5.1

3.9 ± 3.6

4.1 ± 3.8

Ritualistic behavior

6.4 ± 4.9

5.6 ± 4

5.1 ± 3.8

4.8 ± 3.7

5.3 ± 3.7

5.3 ± 4

6.1 ± 5.5

5.4 ± 3.8

5.2 ± 3.8

Sameness behavior

10.1 ± 7.5 d

8.6 ± 6.2

7.5 ± 5.9

6.9 ± 5.8

7.9 ± 6.1

8 ± 6.1

10 ± 8.7

8.5 ± 6.1

7.6 ± 6

Restricted behavior

5.2 ± 3.1 d

3.9 ± 3.1

3.4 ± 2.6

2.9 ± 2.5

3.6 ± 2.7

3.6 ± 2.8

6 ± 2.4 c

3.8 ± 3.1

3.5 ± 2.6

Sum

35.5 ± 21.7 d

28.8 ± 18.2

25.9 ± 16.3

22.7 ± 14.9

26.9 ± 16.5

27.8 ± 17.8

36.2 ± 21.2

27.4 ± 17

26.6 ± 17

  1. aThe SNP genotypes are based on positive strand.
  2. bTotal number of probands with genotype data available.
  3. Permutation p values: cp < 0.1; dp < 0.05.