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Table 2 The individual SNP genotypes versus RBS-R subscale and sum mean scores

From: A quantitative association study of SLC25A12 and restricted repetitive behavior traits in autism spectrum disorders

UIC-UF sample (n = 179 probands)
SNP rs2056202 rs2056202 rs2056202 rs908670 rs908670 rs908670 rs2292813 rs2292813 rs2292813
Genotypea A/A A/G G/G G/G G/A A/A A/A A/G G/G
Nb 6 66 106 15 76 86 3 52 124
Stereotyped behavior 5.5 ± 3.4 6.6 ± 4 5.3 ± 3.5 7.1 ± 4.6 5.5 ± 3.7 5.8 ± 3.6 4.3 ± 3.2 6.9 ± 3.9 5.4 ± 3.6
Self-injurious behavior 2.2 ± 1.9 4.8 ± 5.6 3.1 ± 3.9 4.2 ± 6.4 3.1 ± 4.2 4.3 ± 4.8 2.3 ± 1.5 5.1 ± 5.7 3.2 ± 4.2
Compulsive behavior 6.5 ± 6.2 6.7 ± 5.3 6.4 ± 5.3 9.5 ± 7.9 6 ± 4.7 6.2 ± 5 4.3 ± 4 7.4 ± 5.6 6.1 ± 5.2
Ritualistic behavior 4.8 ± 3.7 8.3 ± 5.5 c 5.9 ± 4.2 6.1 ± 4.8 6.4 ± 4.8 7 ± 5 3.3 ± 3.5 8.8 ± 5.3 d 5.9 ± 4.4
Sameness behavior 10.2 ± 8.3 12.9 ± 8.6 9.9 ± 6.6 10.5 ± 7.5 10.4 ± 7.1 11.5 ± 7.8 10 ± 11.4 13.8 ± 8.7 d 9.9 ± 6.7
Restricted behavior 3.7 ± 3.6 5.8 ± 3.4 4.9 ± 3.1 5.1 ± 3.6 5.1 ± 3.5 5.4 ± 3.1 3.3 ± 3.2 6.3 ± 3.4 4.8 ± 3.2
Sum 32.8 ± 21.9 45.8 ± 26.5 35.4 ± 19.6 42.6 ± 24.5 36 ± 21.8 41.2 ± 23.2 27.7 ± 22.7 48.5 ± 26d 35.5 ± 20.2
SSC sample (n = 720 probands)
SNP rs2056202 rs2056202 rs2056202 rs908670 rs908670 rs908670 rs2292813 rs2292813 rs2292813
Genotypea A/A A/G G/G G/G G/A A/A A/A A/G G/G
Nb 21 176 523 67 284 367 10 127 583
Stereotyped behavior 6 ± 3.6 d 4.4 ± 3.2 4 ± 3.1 3.3 ± 2.8 4.1 ± 3 4.4 ± 3.3 d 5.6 ± 3.8 4.2 ± 2.9 4.1 ± 3.2
Self-injurious behavior 3.8 ± 4.5 d 2.1 ± 2.9 1.9 ± 2.6 1.4 ± 2 1.8 ± 2.4 2.3 ± 3.1 d 2.8 ± 3 2 ± 2.6 2 ± 2.8
Compulsive behavior 5.5 ± 4.8 4.3 ± 3.9 4 ± 3.7 3.3 ± 3 4.1 ± 4 4.3 ± 3.8 5.7 ± 5.1 3.9 ± 3.6 4.1 ± 3.8
Ritualistic behavior 6.4 ± 4.9 5.6 ± 4 5.1 ± 3.8 4.8 ± 3.7 5.3 ± 3.7 5.3 ± 4 6.1 ± 5.5 5.4 ± 3.8 5.2 ± 3.8
Sameness behavior 10.1 ± 7.5 d 8.6 ± 6.2 7.5 ± 5.9 6.9 ± 5.8 7.9 ± 6.1 8 ± 6.1 10 ± 8.7 8.5 ± 6.1 7.6 ± 6
Restricted behavior 5.2 ± 3.1 d 3.9 ± 3.1 3.4 ± 2.6 2.9 ± 2.5 3.6 ± 2.7 3.6 ± 2.8 6 ± 2.4 c 3.8 ± 3.1 3.5 ± 2.6
Sum 35.5 ± 21.7 d 28.8 ± 18.2 25.9 ± 16.3 22.7 ± 14.9 26.9 ± 16.5 27.8 ± 17.8 36.2 ± 21.2 27.4 ± 17 26.6 ± 17
  1. aThe SNP genotypes are based on positive strand.
  2. bTotal number of probands with genotype data available.
  3. Permutation p values: cp < 0.1; dp < 0.05.