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Figure 3 | Molecular Autism

Figure 3

From: Further characterization of autoantibodies to GABAergic neurons in the central nervous system produced by a subset of children with autism

Figure 3

Fluorescence confocal photomicrographs of double-labeling with plasma from a representative child with autism (age 5 years) and an antibody directed at GABA. (A) GABA immunoreactivity in area V1 (green). (B) Immunoreactivity of V1 with plasma from a child with autism (red). (C) Merged images from Figures 3A and 3B showing several double-labeled cells (yellow). The vessels have been labeled (V) to aid in orientation with Figure 3D. (D) Schematic of the same region shown in Figures 3A to 3C, with cells coexpressing GABA and plasma immunoreactivity, depicted as yellow circles, GABAergic cells without plasma immunoreactivity, depicted as green hexagons, and a single GABA-negative, plasma-positive cell, depicted as a red star. The vessels have been labeled (V) to aid in orientation with Figure 3C. Calibration bar, 100 μm.

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