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Table 3 Results for SNPs with replication and meta- and joint analysis P values < 0.05 and within candidate genes or regions

From: An X chromosome-wide association study in autism families identifies TBL1X as a novel autism spectrum disorder candidate gene in males

Marker

Map position (bp)

Minor/major allele

MAFa

Discovery

Validation

Meta

Joint

Test

Gene

rs721699

32,468,253

T/C

0.384

7.45 × 10-3

4.72 × 10-2

9.57 × 10-4

5.70 × 10-4

Overall

DMD

rs9887672

104,882,811

T/C

0.103

2.17 × 10-2

1.53 × 10-3

1.28 × 10-4

1.20 × 10-3

Male

IL1RAPL2

rs10218388

104,875,605

C/T

0.107

3.08 × 10-2

2.64 × 10-3

2.94 × 10-4

2.5 × 10-4

Male

IL1RAPL2

rs5962575

104,868,160

C/T

0.107

3.44 × 10-2

2.19 × 10-3

2.86 × 10-4

2.30 × 10-4

Male

IL1RAPL2

  1. aMinor allele frequency (MAF) estimated on the basis of the discovery data set. DMD = Dystrophin Duchenne muscular dystrophy gene; IL1RAPL2 = IL-1 receptor accessory protein-like 2 gene.