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Table 2 Results for the SNPs that survived chromosome-wide multiple testing in the meta- and joint analyses and for the two neighboring significant SNPs

From: An X chromosome-wide association study in autism families identifies TBL1X as a novel autism spectrum disorder candidate gene in males

Marker

Map position (bp)

Minor/major allele

MAFa

Discovery

Validation

Meta

Joint

Test

Gene

rs5934665

9,570,450

G/A

0.433

2.87 × 10-3

1.87 × 10-3

1.77 × 10-5

3.00 × 10-5

Male

TBL1X

rs5934665

9,570,450

G/A

0.449

2.46 × 10-1

3.24 × 10-1

8.59 × 10-1

4.67 × 10-1

Female

TBL1X

rs17321050

9,573,099

G/T

0.335

5.89 × 10-3

2.56 × 10-4

4.86 × 10-6

4.53 × 10-6

Male

TBL1X

rs17321050

9,573,099

G/T

0.359

1.99 × 10-1

5.22 × 10-1

6.15 × 10-1

3.85 × 10-1

Female

TBL1X

rs2188766

9,574,739

C/T

0.432

4.33 × 10-3

4.42 × 10-4

7.76 × 10-6

2.00 × 10-5

Male

TBL1X

rs2188766

9,574,739

C/T

0.451

2.34 × 10-1

3.80 × 10-1

7.86 × 10-1

4.21 × 10-1

Female

TBL1X

  1. aMinor allele frequency (MAF) estimated on the basis of the discovery data set. TBL1X = transducin β-like 1X-linked gene.