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Table 1 Risk allele frequency (defined as the allele associated with autism)

From: Autism risk assessment in siblings of affected children using sex-specific genetic scores

Gene SNP Risk allele Exploratory sample Replication sample
    Frequency HWEa Frequency HWEa
MARK1 rs12410279 A 0.85 0.26 0.83 1.00
SLC25A12 rs2292813 C 0.90 1.00 NEb NE
ATP2B2 rs2278556 A 0.40 0.68 0.38 0.11
PITX1 rs6872664 C 0.89 1.00 0.85 0.32
GRIK2 rs2235076 G 0.98 1.00 NE NE
HOXA1 rs10951154 T 0.86 0.02 0.86 1.00
CNTNAP2 rs7794745 T 0.40 0.73 0.39 0.04
EN2 rs1861972 A 0.73 0.68 0.76 0.90
ITGB3 rs5918 T 0.87 1.00 0.85 0.85
JARID2 rs7766973 C 0.60 0.22 0.58 0.76
  1. aHardy-Weinberg Equilibrium (HWE) P value estimated with the exact test [65].
  2. bNE, not estimated since not genotyped in the replication sample.
  3. SNP, single nucleotide polymorphism.