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Table 1 Risk allele frequency (defined as the allele associated with autism)

From: Autism risk assessment in siblings of affected children using sex-specific genetic scores

Gene

SNP

Risk allele

Exploratory sample

Replication sample

   

Frequency

HWEa

Frequency

HWEa

MARK1

rs12410279

A

0.85

0.26

0.83

1.00

SLC25A12

rs2292813

C

0.90

1.00

NEb

NE

ATP2B2

rs2278556

A

0.40

0.68

0.38

0.11

PITX1

rs6872664

C

0.89

1.00

0.85

0.32

GRIK2

rs2235076

G

0.98

1.00

NE

NE

HOXA1

rs10951154

T

0.86

0.02

0.86

1.00

CNTNAP2

rs7794745

T

0.40

0.73

0.39

0.04

EN2

rs1861972

A

0.73

0.68

0.76

0.90

ITGB3

rs5918

T

0.87

1.00

0.85

0.85

JARID2

rs7766973

C

0.60

0.22

0.58

0.76

  1. aHardy-Weinberg Equilibrium (HWE) P value estimated with the exact test [65].
  2. bNE, not estimated since not genotyped in the replication sample.
  3. SNP, single nucleotide polymorphism.