Table 1 Clinical characteristics of the normal controls and subjects with autism.a
From: Investigation of the serum levels of anterior pituitary hormones in male children with autism
| Â | Control group (n = 34) | Autism group (n = 32) | P-value |
|---|---|---|---|
Age, years | 12.4 ± 2.6 (6 to 18) | 12.3 ± 3.2 (6 to 18) | NS |
Weight, kg | 42.3 ± 14.3 (15.6 to 89.3) | 41.8 ± 15.0 (17.5 to 96.6) | NS |
Height, cm | 150.8 ± 14.8 (111 to 174) | 148.7 ± 17.9 (110 to 178) | NS |
BMI, kg/m2 | 18.1 ± 3.5 (12.7 to 32.4) | 18.3 ± 3.1 (13.9 to 30.5) | NS |
ADI-R | Â | Â | Â |
Domain A score | - | 20.2 ± 4.9 (10 to 27) | - |
   Domain BV score | - | 13.6 ± 3.9 (8 to 21) | - |
   Domain C score | - | 5.4 ± 2.0 (3 to 9) | - |
   Domain D score | - | 3.1 ± 1.0 (2 to 5) | - |
WISC-III | Â | Â | Â |
   Verbal IQ | - | 91.3 ± 21.6 (48 to 133) | - |
   Performance IQ | - | 95.3 ± 21.1 (47 to 131) | - |
   Full-scale IQ | - | 91.0 ± 23.2 (44 to 134) | - |
Anterior pituitary hormones | Â | Â | Â |
   ACTH, pg/mL | 7.2 ± 3.1 (3.7 to 14.2) | 11.6 ± 5.1 (3.7 to 26.3) | < 0.001 |
   GH, pg/mL | 1590.1 ± 2447.5 (34.8 to 13708.0) | 6495.4 ± 9072.2 (30.7 to 34811.5) | 0.002 |
   FSH, mIU/mL | 3.8 ± 2.0 (0.8 to 8.1) | 5.7 ± 3.7 (0.6 to 16.4) | NS |
   LH, mIU/mL | 1.4 ± 1.7 (0.1 to 7.1) | 2.5 ± 2.5 (0.1 to 11.8) | NS |
   TSH, μIU/mL | 3.6 ± 1.4 (1.0 to 7.4) | 3.3 ± 2.2 (0.3 to 11.2) | NS |
   PRL, ng/mL | 20.9 ± 9.1 (4.4 to 38.0) | 25.2 ± 14.0 (8.2 to 66.9) | NS |
Cortisol, ng/mL | 58.3 ± 25.3 (16.8 to 116.8) | 74.2 ± 20.0 (23.5 to 101.5) | 0.004 |