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Table 4 Pearson correlation coefficients of cytokines measured in maternal midpregnancy serum in the Early Markers for Autism studya

From: Increased midgestational IFN-γ, IL-4 and IL-5 in women bearing a child with autism: A case-control study

Measurements ASD (N= 84 ASD regression (N= 17) Early-onset ASD (N= 64) ASD with ID (N= 34) ASD without ID (N= 30) DD (N= 49) GP (N= 159)
Cytokines elevated in ASD        
   IFN-γ and IL-4 0.95** 0.95** 0.81** 0.98** 0.97** 0.05 0.48**
   IFN-γ and IL-5 0.73** 0.97** 0.55** 0.91** 0.87** -0.07 0.38**
   IL-4 and IL-5 0.72** 0.89** 0.83** 0.97** 0.82** 0.41** 0.77**
Cytokines elevated in DD        
   IL-2 and IL-4 0.87** 0.72** 0.62** 0.97** 0.78** 0.57** 0.43**
   IL-2 and IL-6 0.02 0.34 0.18 -0.06 0.34 -0.15 0.24**
   IL-4 and IL-6 0.15 0.46 0.34* -0.09 0.42* 0.13 0.11
  1. aASD: autism spectrum disorder; ID: intellectual disability; DD: developmental delay; GP: general population. **P < 0.0001, *P < 0.05.