Table 4 Autism candidate genes with roles in synaptic function.
Function | Candidate gene (by lowest P-value) |
|---|---|
Synaptogenesis | LRRTM4, SYN3 |
Excitatory/inhibitory balance | KCNIP1, KCNQ1, KCNQ5, KCNJ4, SLC6A13, IQCF1, GABBR2, GRIK4, OAT, KCNN3, GRM3, GCOM1, CACNA2D1, GRM7, ADRB2, KCNH7, KCNIP4, GRIK2, CACNG2, KCNMA1, KCNG1 |
Synaptic plasticity | RIMS1, PTGER2, SLC24A2, NETO1, PTGS2 |
Vesicle exocytosis | PTPRN2, AMPH, RAB11B, SYNPR |
Other | TPH2, CHRNA9, RIMBP2, ATXN1, CHRNB4, NOVA1, SNCAIP, CHRM3 |