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Table 2 Common binding domains of autism candidate genes identified by genome-wide association studies-noise reduction (GWAS-NR).

From: A noise-reduction GWAS analysis implicates altered regulation of neurite outgrowth and guidance in autism

INTERPRO term No. of genes INTERPRO identification P-value1
Immunoglobulin I-set 20 IPR013098 8.97E-06
Cadherin 16 IPR002126 6.98E-05
Cadherin cytoplasmic region 7 IPR000233 1.14E-04
Pleckstrin homology 26 IPR001849 5.03E-04
Immunoglobulin 21 IPR013151 5.61E-04
Immunoglobulin subtype 2 21 IPR003598 6.77E-04
Fibronectin, type III-like fold 19 IPR008957 1.19E-03
Fibronectin, type III 19 IPR003961 1.72E-03
Epidermal growth factor (EGF) 14 IPR006209 3.71E-03
Meprin/A5-protein/PTPmu (MAM) 5 IPR000998 6.78E-03
Protein-tyrosine phosphatase, receptor/non-receptor type 7 IPR000242 7.36E-03
Pleckstrin homology-type 24 IPR001993 7.41E-03
von Willebrand factor, type A 10 IPR002035 7.41E-03
Immunoglobulin-like 35 IPR007110 7.57E-03