Table 5 Power analysis referring to a family-based design for common variants with low penetrance under an additive model.
From: Candidate gene study of HOXB1 in autism spectrum disorder
Allele frequency | Penetrance | Power | ||
|---|---|---|---|---|
AA | AB | BB | ||
0.2 | 0.0 | 0.2 | 0.4 | 0.483 |
0.3 | 0.0 | 0.2 | 0.4 | 0.689 |
0.4 | 0.0 | 0.2 | 0.4 | 0.800 |
0.5 | 0.0 | 0.2 | 0.4 | 0.855 |
0.6 | 0.0 | 0.2 | 0.4 | 0.899 |
0.7 | 0.0 | 0.2 | 0.4 | 0.902 |
0.2 | 0.0 | 0.15 | 0.3 | 0.351 |
0.3 | 0.0 | 0.15 | 0.3 | 0.511 |
0.4 | 0.0 | 0.15 | 0.3 | 0.637 |
0.5 | 0.0 | 0.15 | 0.3 | 0.730 |
0.6 | 0.0 | 0.15 | 0.3 | 0.795 |
0.7 | 0.0 | 0.15 | 0.3 | 0.735 |
0.2 | 0.0 | 0.1 | 0.2 | 0.202 |
0.3 | 0.0 | 0.1 | 0.2 | 0.277 |
0.4 | 0.0 | 0.1 | 0.2 | 0.396 |
0.5 | 0.0 | 0.1 | 0.2 | 0.477 |
0.6 | 0.0 | 0.1 | 0.2 | 0.488 |
0.7 | 0.0 | 0.1 | 0.2 | 0.505 |