Skip to main content

Table 4 Case-control study for the HOXB1 polymorphisms rs72338773 [c.82insACAGCGCCC (INS/nINS)] and rs12939811 [c.309A>T (Q103H)].

From: Candidate gene study of HOXB1 in autism spectrum disorder

Genotypes Italian patients (N= 169) Italian controls (N= 184) Alleles Italian patients (N= 338) Italian controls (N= 368)
nINS/nINS 100 (59.2%) 125 (67.9%) nINS 262 (0.7751) 303 (0.8234)
nINS/INS 62 (36.7%) 53 (28.8%) INS 76 (0.2249) 65 (0.1766)
INS/INS 7 (4.1%) 6 (3.3%)    
  χ2 = 2.93, 2 df, P = 0.23, ns   Exact 2-tail P = 0.13, ns
A/A 102 (60.4%) 125 (67.9%) A 263 (0.7781) 304 (0.8261)
A/T 59 (34.9%) 54 (29.3%) T 75 (0.2219) 64 (0.1739)
T/T 8 (4.7%) 5 (2.8%)    
  χ2 = 2.61, 2 df, P = 0.27, ns   Exact two-tail P = 0.13, ns
  1. INS, insertion; ns, not significant.