Table 4 Case-control study for the HOXB1 polymorphisms rs72338773 [c.82insACAGCGCCC (INS/nINS)] and rs12939811 [c.309A>T (Q103H)].
From: Candidate gene study of HOXB1 in autism spectrum disorder
Genotypes | Italian patients (N= 169) | Italian controls (N= 184) | Alleles | Italian patients (N= 338) | Italian controls (N= 368) |
|---|---|---|---|---|---|
nINS/nINS | 100 (59.2%) | 125 (67.9%) | nINS | 262 (0.7751) | 303 (0.8234) |
nINS/INS | 62 (36.7%) | 53 (28.8%) | INS | 76 (0.2249) | 65 (0.1766) |
INS/INS | 7 (4.1%) | 6 (3.3%) | Â | Â | Â |
|  | χ2 = 2.93, 2 df, P = 0.23, ns |  | Exact 2-tail P = 0.13, ns | ||
A/A | 102 (60.4%) | 125 (67.9%) | A | 263 (0.7781) | 304 (0.8261) |
A/T | 59 (34.9%) | 54 (29.3%) | T | 75 (0.2219) | 64 (0.1739) |
T/T | 8 (4.7%) | 5 (2.8%) | Â | Â | Â |
|  | χ2 = 2.61, 2 df, P = 0.27, ns |  | Exact two-tail P = 0.13, ns | ||