Table 4 Genetic score sensitivities and specificities predicting autism in siblings of affected children.
From: Assessing the impact of a combined analysis of four common low-risk genetic variants on autism risk
Genetic score | AGRE sample | Seattle sample | ||
|---|---|---|---|---|
| Â | Sensitivity (95% CI) | Specificity (95% CI) | Sensitivity (95% CI) | Specificity (95% CI) |
2* | 1.00 | 0.00 | 1.00 | 0.00 |
3 | 0.99 (0.98 to 1.00) | 0.02 (0.00 to 0.03) | 0.99 (0.97 to 1.00) | 0.01 (0.00 to 0.03) |
4 | 0.94 (0.92 to 0.97) | 0.06 (0.03 to 0.09) | 0.95 (0.92 to 0.98) | 0.04 (0.00 to 0.07) |
5 | 0.81 (0.76 to 0.86) | 0.26 (0.21 to 0.31) | 0.81 (0.75 to 0.87) | 0.26 (0.18 to 0.35) |
6 | 0.50 (0.44 to 0.56) | 0.67 (0.61 to 0.73) | 0.50 (0.43 to 0.57) | 0.65 (0.55 to 0.74) |
7 | 0.19 (0.14 to 0.25) | 0.91 (0.87 to 0.96) | 0.17 (0.12 to 0.22) | 0.93 (0.87 to 0.98) |
8 | 0.09 (0.05 to 0.12) | 0.98 (0.96 to 1.00) | 0.08 (0.04 to 0.12) | 0.98 (0.96 to 1.00) |