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Table 1 Correlations of IS and RSMA with ADI-R, ADOS, SRS and IQ measures.

From: Genome-wide linkage analyses of two repetitive behavior phenotypes in Utah pedigrees with autism spectrum disorders

Criterion

IS

RSMA

t-Test

 

Raw

Res

Raw

Res

IS vs. RSMA

IS vs. IS-Adj

RSMA vs. RSMA-Adj

ADI-R Social

0.30*

0.12

0.57*

0.50*

3.75*

8.98*

3.62*

ADI-R Comm

0.41*

0.27*

0.49*

0.40*

0.98

6.09*

4.19*

ADI-R RRSB

0.63*

0.46*

0.61*

0.42*

0.46

10.95*

11.77*

ADOS Score†

- 0.01

- 0.10

0.29*

0.31*

3.60*

3.88*

0.87

SRS Mannerisms

0.29*

0.11

0.57*

0.51*

3.70*

8.60*

3.03*

First words

-0.02

- 0.06

0.12

0.14

1.43

1.51

0.52

First phrases

0.10

0.03

0.22*

0.21*

1.18

2.26

0.36

VIQ

0.10

0.23*

- 0.38*

- 0.43*

5.52*

5.48*

2.09

NVIQ

0.17

0.30*

- 0.37*

- 0.45*

6.42*

5.68*

3.31*

FSIQ

0.11

0.25*

- 0.41*

- 0.47*

6.26*

6.25*

2.56

  1. ADI-R Comm, verbal communication; ADOS, Autism Diagnostic Observation Schedule; FSIQ, full scale IQ; IS, insistence on sameness; IS-Adj, IS adjusted for RSMA; NVIQ, nonverbal IQ; RRSB, restricted and repetitive stereotyped behavior; RSMA, repetitive sensory-motor actions; RSMA-Adj, RSMA adjusted for IS; SRS, Social Reciprocity Scale; VIQ, verbal IQ.
  2. *P < 0.01.
  3. †For ADOS score, partial correlations with ADOS 'module' effects removed are reported.
  4. The t-tests are two-tailed tests of the difference between correlations with the same criterion variable [70]. Sample sizes ranged from 131 to181, depending criterion variable.
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Molecular Autism

ISSN: 2040-2392