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  1. Research

    Glutathione metabolism in the prefrontal brain of adults with high-functioning autism spectrum disorder: an MRS study

    Autism spectrum disorder (ASD) is a neurodevelopmental disease characterized by difficulties in social communication, unusually restricted, repetitive behavior and interests, and specific abnormalities in lang...

    Dominique Endres, Ludger Tebartz van Elst, Simon A. Meyer, Bernd Feige, Kathrin Nickel, Anna Bubl, Andreas Riedel, Dieter Ebert, Thomas Lange, Volkmar Glauche, Monica Biscaldi, Alexandra Philipsen, Simon J. Maier and Evgeniy Perlov

    Molecular Autism 2017 8:10

    Published on: 7 March 2017

  2. Research

    Neural circuitry at age 6 months associated with later repetitive behavior and sensory responsiveness in autism

    Restricted and repetitive behaviors are defining features of autism spectrum disorder (ASD). Under revised diagnostic criteria for ASD, this behavioral domain now includes atypical responses to sensory stimuli...

    Jason J. Wolff, Meghan R. Swanson, Jed T. Elison, Guido Gerig, John R. Pruett Jr., Martin A. Styner, Clement Vachet, Kelly N. Botteron, Stephen R. Dager, Annette M. Estes, Heather C. Hazlett, Robert T. Schultz, Mark D. Shen, Lonnie Zwaigenbaum and Joseph Piven

    Molecular Autism 2017 8:8

    Published on: 4 March 2017

  3. Research

    Disconnection from others in autism is more than just a feeling: whole-brain neural synchrony in adults during implicit processing of emotional faces

    Socio-emotional difficulties in autism spectrum disorder (ASD) are thought to reflect impaired functional connectivity within the “social brain”. Nonetheless, a whole-brain characterization of the fast respons...

    Rocco Mennella, Rachel C. Leung, Margot J. Taylor and Benjamin T. Dunkley

    Molecular Autism 2017 8:7

    Published on: 22 February 2017

  4. Research

    Exaggerated CpH methylation in the autism-affected brain

    The etiology of autism, a complex, heritable, neurodevelopmental disorder, remains largely unexplained. Given the unexplained risk and recent evidence supporting a role for epigenetic mechanisms in the develop...

    Shannon E. Ellis, Simone Gupta, Anna Moes, Andrew B. West and Dan E. Arking

    Molecular Autism 2017 8:6

    Published on: 17 February 2017

  5. Short Report

    Possible sexually dimorphic role of miRNA and other sncRNA in ASD brain

    Autism spectrum disorder (ASD) is sexually dimorphic in brain structure, genetics, and behaviors. In studies of brain tissue, the age of the population is clearly a factor in interpreting study outcome, yet se...

    Cynthia M. Schumann, Frank R. Sharp, Bradley P. Ander and Boryana Stamova

    Molecular Autism 2017 8:4

    Published on: 7 February 2017

  6. Research

    Umbilical cord blood androgen levels and ASD-related phenotypes at 12 and 36 months in an enriched risk cohort study

    Autism spectrum disorder (ASD) affects more than 1% of children in the USA. The male-to-female prevalence ratio of roughly 4:1 in ASD is a well-recognized but poorly understood phenomenon. An explicit focus on...

    Bo Y. Park, Brian K. Lee, Igor Burstyn, Loni P. Tabb, Jeff A. Keelan, Andrew J. O. Whitehouse, Lisa A. Croen, Margaret D. Fallin, Irva Hertz-Picciotto, Owen Montgomery and Craig J. Newschaffer

    Molecular Autism 2017 8:3

    Published on: 31 January 2017

  7. Research

    d-Cycloserine enhances durability of social skills training in autism spectrum disorder

    d-Cycloserine (DCS) enhances extinction learning across species, but it has proven challenging to identify consistent benefit of DCS when added to therapeutic interventions. We conduct...

    Logan K. Wink, Noha F. Minshawi, Rebecca C. Shaffer, Martin H. Plawecki, David J. Posey, Paul S. Horn, Ryan Adams, Ernest V. Pedapati, Tori L. Schaefer, Christopher J. McDougle, Naomi B. Swiezy and Craig A. Erickson

    Molecular Autism 2017 8:2

    Published on: 25 January 2017

  8. Research

    Serum and cerebrospinal fluid immune mediators in children with autistic disorder: a longitudinal study

    The causes of autism likely involve genetic and environmental factors that influence neurobiological changes and the neurological and behavioral features of the disorder. Immune factors and inflammation are hy...

    Carlos A. Pardo, Cristan A. Farmer, Audrey Thurm, Fatma M. Shebl, Jorjetta Ilieva, Simran Kalra and Susan Swedo

    Molecular Autism 2017 8:1

    Published on: 5 January 2017

  9. Research

    Basic and complex emotion recognition in children with autism: cross-cultural findings

    Children with autism spectrum conditions (ASC) have emotion recognition deficits when tested in different expression modalities (face, voice, body). However, these findings usually focus on basic emotions, usi...

    Shimrit Fridenson-Hayo, Steve Berggren, Amandine Lassalle, Shahar Tal, Delia Pigat, Sven Bölte, Simon Baron-Cohen and Ofer Golan

    Molecular Autism 2016 7:52

    Published on: 19 December 2016

  10. Research

    Placental methylome analysis from a prospective autism study

    Autism spectrum disorders (ASD) are increasingly prevalent neurodevelopmental disorders that are behaviorally diagnosed in early childhood. Most ASD cases likely arise from a complex mixture of genetic and env...

    Diane I. Schroeder, Rebecca J. Schmidt, Florence K. Crary-Dooley, Cheryl K. Walker, Sally Ozonoff, Daniel J. Tancredi, Irva Hertz-Picciotto and Janine M. LaSalle

    Molecular Autism 2016 7:51

    Published on: 15 December 2016

  11. Research

    Bengali translation and characterisation of four cognitive and trait measures for autism spectrum conditions in India

    Autism is characterised by atypical social-communicative behaviour and restricted range of interests and repetitive behaviours. These features exist in a continuum in the general population. Behavioural measur...

    Alokananda Rudra, Jai Ranjan Ram, Tom Loucas, Matthew K. Belmonte and Bhismadev Chakrabarti

    Molecular Autism 2016 7:50

    Published on: 3 December 2016

  12. Research

    Blood–brain barrier and intestinal epithelial barrier alterations in autism spectrum disorders

    Autism spectrum disorders (ASD) are complex conditions whose pathogenesis may be attributed to gene–environment interactions. There are no definitive mechanisms explaining how environmental triggers can lead t...

    Maria Fiorentino, Anna Sapone, Stefania Senger, Stephanie S. Camhi, Sarah M. Kadzielski, Timothy M. Buie, Deanna L. Kelly, Nicola Cascella and Alessio Fasano

    Molecular Autism 2016 7:49

    Published on: 29 November 2016

  13. Research

    Dyspraxia and autistic traits in adults with and without autism spectrum conditions

    Autism spectrum conditions (ASC) are frequently associated with motor coordination difficulties. However, no studies have explored the prevalence of dyspraxia in a large sample of individuals with and without ...

    Sarah Cassidy, Penelope Hannant, Teresa Tavassoli, Carrie Allison, Paula Smith and Simon Baron-Cohen

    Molecular Autism 2016 7:48

    Published on: 25 November 2016

  14. Short report

    Mimetic desire in autism spectrum disorder

    Mimetic desire (MD), the spontaneous propensity to pursue goals that others pursue, is a case of social influence that is believed to shape preferences. Autism spectrum disorder (ASD) is defined by both atypic...

    Baudouin Forgeot d’Arc, Fabien Vinckier, Maël Lebreton, Isabelle Soulières, Laurent Mottron and Mathias Pessiglione

    Molecular Autism 2016 7:45

    Published on: 8 November 2016

  15. Research

    Altered functional organization within the insular cortex in adult males with high-functioning autism spectrum disorder: evidence from connectivity-based parcellation

    The insular cortex comprises multiple functionally differentiated sub-regions, each of which has different patterns of connectivity with other brain regions. Such diverse connectivity patterns are thought to u...

    Takashi Yamada, Takashi Itahashi, Motoaki Nakamura, Hiromi Watanabe, Miho Kuroda, Haruhisa Ohta, Chieko Kanai, Nobumasa Kato and Ryu-ichiro Hashimoto

    Molecular Autism 2016 7:41

    Published on: 5 October 2016

  16. Research

    Quantitative autistic trait measurements index background genetic risk for ASD in Hispanic families

    Recent studies have indicated that quantitative autistic traits (QATs) of parents reflect inherited liabilities that may index background genetic risk for clinical autism spectrum disorder (ASD) in their offsp...

    Joshua Page, John Nicholas Constantino, Katherine Zambrana, Eden Martin, Ilker Tunc, Yi Zhang, Anna Abbacchi and Daniel Messinger

    Molecular Autism 2016 7:39

    Published on: 6 September 2016

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